Warning: fopen(/home/virtual/epih/journal/upload/ip_log/ip_log_2024-07.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 95 Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 96 Comparison of HIV characteristics across 3 datasets: the Korea HIV/AIDS Cohort Study Prospective, Retrospective, and National Reporting System
Skip Navigation
Skip to contents

Epidemiol Health : Epidemiology and Health

OPEN ACCESS
SEARCH
Search

Articles

Page Path
HOME > Epidemiol Health > Accepted Articles > Article
Original article Comparison of HIV characteristics across 3 datasets: the Korea HIV/AIDS Cohort Study Prospective, Retrospective, and National Reporting System
Yunsu Choi1,2orcid , Jun Yong Choi3orcid , Bo Youl Choi1,2orcid , Bo Young Park1,2orcid , Shin-Woo Kim4orcid , Joon Young Song5orcid , Jung Ho Kim3orcid , Sang Il Kim6orcid
Epidemiol Health 2024;e2024055
DOI: https://doi.org/10.4178/epih.e2024055 [Accepted]
Published online: June 18, 2024
1Department of Preventive Medicine, College of Medicine, Hanyang University, Seoul, Korea
2Institute for Health and Society, Hanyang University, Seoul, Korea
3Department of Internal Medicine, Yonsei University College of Medicine AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea
4Department of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Korea
5Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
6Division of Infectious Disease, Department of Internal Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
Corresponding author:  Bo Youl Choi,
Email: drksi@catholic.ac.kr
Sang Il Kim,
Email: drksi@catholic.ac.kr
Received: 20 September 2023   • Revised: 6 April 2024   • Accepted: 15 May 2024
  • 495 Views
  • 28 Download
  • 0 Crossref
  • 0 Scopus

OBJECTIVES
The Korea HIV/AIDS Cohort Study has been conducted prospectively for 18 years. However, it faces limitations in representing the entire population of patients with HIV in Korea. To address these limitations and validate the study design, we analyzed characteristics across several HIV datasets.
METHODS
We compared epidemiological and clinical characteristics from 3 datasets: the Korea HIV/AIDS Cohort Study (dataset 1, n=1,562), retrospective cohort data (dataset 2, n=2,665), and the national HIV reporting system of the Korea Disease Control and Prevention Agency (KDCA) (dataset 3, n=17,403).
RESULTS
The demographic characteristics of age, sex, and age at HIV diagnosis did not differ significantly across datasets. However, dataset 3 contained a higher percentage of patients diagnosed after 2008 (69.5%) than the other datasets. Regarding transmission routes, same-sex contact accounted for a greater proportion of dataset 1 (59.8%) compared to datasets 2 (20.9%) and 3 (32.6%). The percentage of patients with CD4 T-cell counts below 200/mm3 at HIV diagnosis was higher in datasets 1 (39.4%) and 2 (33.3%) compared to dataset 3 (16.3%). Initial HIV viral load measurements were not obtained for dataset 3.
CONCLUSIONS
The Korea HIV/AIDS Cohort Study demonstrated representativeness regarding the demographic characteristics of Korean patients. Of the sources, dataset 1 contained the most data on transmission routes. While the KDCA data encompassed all HIV patients, it lacked detailed clinical information. To improve the representativeness of the Korea HIV/AIDS Cohort Study, we propose expanding and revising the cohort design and enrolling more patients who have been recently diagnosed.


Epidemiol Health : Epidemiology and Health